Rage Against The Machine were forced to stanch their headline set on the Main Stage at Leeds Festival tonight (August 23) to prevent a crowd crush.
The band stopped abruptly nigh the end of fourth track 'Bombtrack', and isaac M. Singer Zack de la Rocha asked the crowd to all pack a few steps back.
It is believed a jam was seen to be developing in the audience by security measures, who informed the band of the situation in order to avoid whatever injury.
Rage Against The Machine paused their put for about three minutes while the crowd stirred back, then launched fiercely back into 'Bombtrack' where they had left off.
The band took to the stage in their usual clothes tonight, rather than the Guantanamo-style boilersuits they came on with at Reading Festival last night (August 22).
The setlist was also slightly different from last night, omitting fan favourite 'Wake Up' and adding in tracks such as 'Renegades Of Funk' and 'Down Rodeo'.
Frontman de la Rocha said little passim the coif, which byword a massive crowd - who regularly gasped and cheered at Tom Morello's guitarwork - turn up to see the ring, .
The band linked blazon and raised fists as they left hand the stage after the band's regular closer and crowd favourite 'Killing In The Name'.
Rage Against The Machine played:
'Testify'
'Bulls On Parade'
'People Of The Sun'
'Bombtrack'
'Know Your Enemy'
'Bullet In The Head'
'Renegades Of Funk'
'Guerilla Radio'
'Down Rodeo'
'Calm Like A Bomb'
'Sleep Now In The Fire'
'War Within A Breath'
'Freedom'
'Killing In The Name'
NME.COM is bringing you live insurance coverage straight from both sites of the Reading And Leeds Festivals 2008. For the latest news, blogs, pictures and video interviews head to the Reading And Leeds Festivals index finger now.
Plus have sure you get next week's progeny of NME - on newsstands countrywide from Wednesday August 27 - for the ultimate Reading And Leeds Festivals review.
For more Reading And Leeds Festivals coverage including live footage and more, visit fellow official media partner bbc.co.uk/readingandleeds.
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Tuesday, 26 August 2008
Saturday, 16 August 2008
Some Types Of Leukemia Are Addicted To Notch Proteins
�The leukemic cells in a tumid proportion of individuals with a variant of leucaemia known as T-ALL receive mutations in the NOTCH1 gene. These mutations lede to the generation of Notch1 proteins that have increased body process, however, it is non known whether they have sufficient increased activity to actually initiate the disease.
New data, generated by a team of researchers, at the University of Pennsylvania School of Medicine, Philadelphia, and Brigham and Women's Hospital, Boston, have now indicated that only uncommon T-ALL-associated NOTCH1 mutations have the ability to induce cells to become leukemic in mice (these uncommon mutations generated Notch1 proteins with far greater increased activity than the Notch1 proteins generated by the more common mutations).
However, although the more than common mutations were non themselves able to cause cells to become leukemic in mice, they were able to accelerate the onset of leukemia induced by other genetic mutations.
The authors therefore indicate that all T-ALL leukemic cells with mutations in the NOTCH1 gene ar "addicted" to Notch and that this study provides support for the rating of Notch signaling pathway inhibitors as a treatment for cancer of the blood.
"Leukemia-associated NOTCH1 alleles ar weak tumour initiators just accelerate K-ras-initiated leukemia"
Mark Y. Chiang, Lanwei Xu, Olga Shestova, Gavin Histen, Sarah L'Heureux, Candice Romany, M. Eden Childs, Phyllis A. Gimotty, Jon C. Aster and Warren S. Pear
J. Clin. Invest. doi:10.1172/JCI35090
Click here to view clause online
The Journal of Clinical Investigation (JCI) is the publication of the American Society for Clinical Investigation, an honor society of physician-scientists.
www.jci.org
More info
New data, generated by a team of researchers, at the University of Pennsylvania School of Medicine, Philadelphia, and Brigham and Women's Hospital, Boston, have now indicated that only uncommon T-ALL-associated NOTCH1 mutations have the ability to induce cells to become leukemic in mice (these uncommon mutations generated Notch1 proteins with far greater increased activity than the Notch1 proteins generated by the more common mutations).
However, although the more than common mutations were non themselves able to cause cells to become leukemic in mice, they were able to accelerate the onset of leukemia induced by other genetic mutations.
The authors therefore indicate that all T-ALL leukemic cells with mutations in the NOTCH1 gene ar "addicted" to Notch and that this study provides support for the rating of Notch signaling pathway inhibitors as a treatment for cancer of the blood.
"Leukemia-associated NOTCH1 alleles ar weak tumour initiators just accelerate K-ras-initiated leukemia"
Mark Y. Chiang, Lanwei Xu, Olga Shestova, Gavin Histen, Sarah L'Heureux, Candice Romany, M. Eden Childs, Phyllis A. Gimotty, Jon C. Aster and Warren S. Pear
J. Clin. Invest. doi:10.1172/JCI35090
Click here to view clause online
The Journal of Clinical Investigation (JCI) is the publication of the American Society for Clinical Investigation, an honor society of physician-scientists.
www.jci.org
More info
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Thursday, 7 August 2008
Delta Goodrem: Elevation
When Delta Goodrem was cast in Australia's long-running serial "Neighbours" in 2002, the adolescent didn't care for the "bad girl" character written for her -- and had the audacity to renege on the potentially career-making persona.
Goodrem had already signed a development deal with Sony Records and felt the part didn't suit the hopeful tone of her music. "It's hard now to believe I had the courage to do that," the 23-year-old says. But as it turns out, show producers wanted to fly with Delta and rewrote the role of shy coffee-shop staffer/budding singer "Nina Tucker" to her liking�and she signed on.
Goodrem has certainly made good on not being bad�but her story has since played out with more real-life melodrama than any soap. When her latest album, "Delta," arrives July 15, it will represent the culmination of five topsy-turvy years.
Her first single "Born to Try" (Columbia)�introduced on "Neighbours" in 2003�rallied to No. 1 at home in Oz, while her debut album "Innocent Eyes" spent 29 weeks as a chart-topper, selling 14-times platinum and winning seven Australian Recording Industry Assn. Awards. The record also made her a star in the United Kingdom, Ireland, Greece, Sweden and Japan.
And then her career came to a precipitous halt when late that year, at 18, she was diagnosed with Hodgkin's lymphoma, a cancer that attacks the immune system. A U.S. launch on Columbia was compromised; single "Lost Without You" reached No. 18 at AC, but too weak to promote it, Goodrem's planned album was scrapped.
After chemotherapy and radiation, her 2004 sophomore CD "Mistaken Identity" was released in established territories and, not surprisingly, displayed a starker lyrical side. Goodrem says, "I was young, but never na�ve, and found strength as a woman. I know it was intense, even tiring." Fans stood alongside (even as she retired from "Neighbours"), with another No. 1. Then, "Delta" in 2007 became her third consecutive chart-topping disc. "The title reflects that I'm my own person now, I've learned a lot," she says. "You can only control so much in life."
Now, she returns to the States�all told with a string of eight No. 1s among 13 top 40 Australian singles to date. Signed to Mercury's resurrected imprint Decca in the U.S., Goodrem has a mighty proponent in label president David Massey�a former global A&R exec for Sony who was integral in grooming her in 2002.
It's a slightly reconfigured "Delta" arriving Stateside. The first single, the uptempo, piano-fervent "In This Life"�produced by Grammy Award winner John Shanks and co-written by Goodrem and fianc� Bryan McFadden (formerly of hitmaking Irish boy band Westlife)�is bulleted at No. 35 at adult top 40. She's partnered with ION Television for its fall launch, including on-air imaging and exposure of "In This Life" and "Believe Again" (a No. 2 single in Oz). She'll appear at the American Cancer Society's fall charity Dreamball and the Jorge Posada Foundation's seventh annual Heroes of Hope Gala, hosted by Kelly Ripa, both in New York.
In addition, Goodrem recorded a duet, "Right Here With You," with fellow Aussie and cancer survivor Olivia Newton-John for the July album release "Olivia Newton-John & Friends: A Celebration in Song," with proceeds to benefit her Cancer and Wellness Centre.
"It's even more rewarding that I get to come back and start properly," Goodrem says of her U.S. relaunch. "I'm hungry for this and committed to being a new artist. I feel like I was always meant to do this, like there's a chip in my body that says, 'OK, what's next?'"
Additional reporting by Christie Eliezer in Melbourne and Andre Paine in London.
More info
Goodrem had already signed a development deal with Sony Records and felt the part didn't suit the hopeful tone of her music. "It's hard now to believe I had the courage to do that," the 23-year-old says. But as it turns out, show producers wanted to fly with Delta and rewrote the role of shy coffee-shop staffer/budding singer "Nina Tucker" to her liking�and she signed on.
Goodrem has certainly made good on not being bad�but her story has since played out with more real-life melodrama than any soap. When her latest album, "Delta," arrives July 15, it will represent the culmination of five topsy-turvy years.
Her first single "Born to Try" (Columbia)�introduced on "Neighbours" in 2003�rallied to No. 1 at home in Oz, while her debut album "Innocent Eyes" spent 29 weeks as a chart-topper, selling 14-times platinum and winning seven Australian Recording Industry Assn. Awards. The record also made her a star in the United Kingdom, Ireland, Greece, Sweden and Japan.
And then her career came to a precipitous halt when late that year, at 18, she was diagnosed with Hodgkin's lymphoma, a cancer that attacks the immune system. A U.S. launch on Columbia was compromised; single "Lost Without You" reached No. 18 at AC, but too weak to promote it, Goodrem's planned album was scrapped.
After chemotherapy and radiation, her 2004 sophomore CD "Mistaken Identity" was released in established territories and, not surprisingly, displayed a starker lyrical side. Goodrem says, "I was young, but never na�ve, and found strength as a woman. I know it was intense, even tiring." Fans stood alongside (even as she retired from "Neighbours"), with another No. 1. Then, "Delta" in 2007 became her third consecutive chart-topping disc. "The title reflects that I'm my own person now, I've learned a lot," she says. "You can only control so much in life."
Now, she returns to the States�all told with a string of eight No. 1s among 13 top 40 Australian singles to date. Signed to Mercury's resurrected imprint Decca in the U.S., Goodrem has a mighty proponent in label president David Massey�a former global A&R exec for Sony who was integral in grooming her in 2002.
It's a slightly reconfigured "Delta" arriving Stateside. The first single, the uptempo, piano-fervent "In This Life"�produced by Grammy Award winner John Shanks and co-written by Goodrem and fianc� Bryan McFadden (formerly of hitmaking Irish boy band Westlife)�is bulleted at No. 35 at adult top 40. She's partnered with ION Television for its fall launch, including on-air imaging and exposure of "In This Life" and "Believe Again" (a No. 2 single in Oz). She'll appear at the American Cancer Society's fall charity Dreamball and the Jorge Posada Foundation's seventh annual Heroes of Hope Gala, hosted by Kelly Ripa, both in New York.
In addition, Goodrem recorded a duet, "Right Here With You," with fellow Aussie and cancer survivor Olivia Newton-John for the July album release "Olivia Newton-John & Friends: A Celebration in Song," with proceeds to benefit her Cancer and Wellness Centre.
"It's even more rewarding that I get to come back and start properly," Goodrem says of her U.S. relaunch. "I'm hungry for this and committed to being a new artist. I feel like I was always meant to do this, like there's a chip in my body that says, 'OK, what's next?'"
Additional reporting by Christie Eliezer in Melbourne and Andre Paine in London.
More info
Monday, 30 June 2008
Pixar - Wall-e Straight In At Number One In Us Box Office
WALL-E, the animated film about a waste compacting robot, has stormed to the top of the US box office in its first week on release.
The Pixar film took $62.5 million (£31.3 million) in its opening weekend.
The film is Pixar's ninth straight number one film and equalled Monsters Inc opening takings.
The Angelina Jolie film Wanted took $51.1 million (£25.6 million) to chart in second place.
While last weekend's number one, Steve Carell's Get Smart, dropped to number three.
Making up the top five films were the Jack Black animated film Kung Fu Panda and Edward Norton's Incredible Hulk.
The comedy Love Guru, starring Mike Myers, claimed the sixth spot and Harrison Ford's return to the iconic role of Indiana Jones with the Kingdom of the Crystal Skull charted at seven this weekend.
The film has now taken almost $300 million (£150 million) in the US alone.
The Happening, Sex and the City and You Don't Mess with the Zohan made up the US top ten.
30/06/2008 11:06:14
See Also
Wednesday, 25 June 2008
Thermo
Artist: Thermo
Genre(s):
Metal
Discography:
Arde En Mi
Year: 2004
Tracks: 11
Mexican goon pretend Thermo were launched in their home town of Guadalajara, Jalisco, in the mid-'90s. Roy Cañedo, Ivan Perez, and Alain Buitrago (the band's beginning guitarist) met in secondary school in 1994, rounded out by Mike iI geezerhood later. The beginning to blaze the emocore trail south of the border, the band developed a reputation for mixing lush vocal harmonies with guttural screams, delicate melodious passages stellar into muscled metallic element riffs. Thermo released their debut, Arde en Mi, without the documentation or guidance of a track record label. Surprisingly, they were able to bring about "major-label" results with an independent button, garnering even airplay and invitations from enceinte venues. The record hit identification number 52 on national charts, an awing acquirement for whatever indie creative person, permit solitary for a number one picnic. As Thermo's fan nucleotide grew and reputation flourished, so did their desire to create a truly unique standout follow-up to their well-loved premiere. The band traveled to Sweden to work out with the crew at Tonteknik recording studios, veteran producers of groups like Cult of Luna, In Flames, and Refused. Mike (keyboards), Ivan (guitars), Kirby (guitars), Meyer (bass), and Roy (drums) were successful in their efforts, scorn finding themselves knocked out on a new artistic branch. The March 2007 release of Bajo el Control del Radar ground favor with national audiences, earning Thermo their beginning time slot on the Billboard charts.
Indy Magnetizes $311.1 Million
Monday, 16 June 2008
Juan Luis Guerra
Artist: Juan Luis Guerra
Genre(s):
Latin
Pop
Other
Latin: Dance
Discography:
La Llave De Mi Corazon
Year: 2007
Tracks: 13
Festival Vina Del Mar 2006
Year: 2006
Tracks: 15
Para Ti
Year: 2004
Tracks: 11
Encuentro
Year: 2002
Tracks: 15
Coleccion Romantica Cd2
Year: 2001
Tracks: 10
Coleccion Romantica Cd1
Year: 2001
Tracks: 10
Ojala Que Llueva Cafe
Year: 2000
Tracks: 8
Mudanza Y Acarreo
Year: 1999
Tracks: 8
Grandes Exitos
Year: 1999
Tracks: 17
Areito
Year: 1999
Tracks: 12
Ni Es Lo Mismo Ni Es Igual
Year: 1998
Tracks: 11
Fogarate
Year: 1994
Tracks: 12
Bachata Rosa
Year: 1991
Tracks: 10
Mientras Mas Lo Pienso
Year: 1986
Tracks: 9
El Original 4.40
Year: 1984
Tracks: 8
Bachata
Year:
Tracks: 4
In his native Dominican Republic, merengue wiz Juan Luis Guerra is considered a poet and musician of the hoi polloi. He and his band 440 ar much loved passim the Latino world and he has become one of the new wave of artists responsible for for revitalizing the tropical music that had been languishing during the tardy '80s from ham and lack of invention.
Guerra is the logos of a professional baseball player and grew up side by side to the National Music Gallery. As a teenager, he was influenced by the Beatles and by the music of the U.S. hipsters. Initially, he taught himself the basics of guitar playacting, just after taking a contest, accompanied the National Conservatory on a scholarship. One of his instructors then helped Guerra catch into the esteemed Berklee College of Music in Massachusetts and the many genres of jazz. In time, he constitute he lost his native Dominican Republic and so returned to experiment with blend local African-influenced music, folks songs and jazz with his group 440. The ring takes its list from the universal joint tuning traffic pattern of the A note, 440 Hertz. The name was chosen by Guerra's comrade José Gilberto wHO victimized to sit and catch them rehearse. One day he commented that they seemed so haunted with staying in perfect melody that they should call themselves that.
Their debut album, Soplando, made little shock. For their future efforts, Mudanza y Acarreo and Mientras Más Lo Pienso Tu, Guerra and 440 began adding merengue and lightning-quick riffs of "perico ripiao," and suddenly constitute success with a cy Young crowd tired from hearing the same quondam thing. The new music, called "bachata-merengue," presently north Korean won considerable acclaim in the Dominican Republic. The mathematical group was selected by their government to represent the nation in the International Music Festival of OTI, the Oraganization of Iberoamerican Television. In 1988, Guerra and 440 had one of their biggest hits, Ojalá Que Llueva Café, which became the third best-selling album in Latin America. That year he mixed-up his lead vocalizer, Maridalia Hernández, wHO left to act on her solo career in Europe, leaving Guerra to turn the new lead vocalizer. In 1991, he released Bachata Rose which became a smash hit passim the Americas and won Guerra his low Grammy in the U.S. The album was particularly popular in Los Angeles and before long Guerra and his ring were touring. His future album, Areito, caused argument in the Dominican Republic for oral presentation tabu against social injustice that the urgently pitiful felt Guerra had never personally experienced. Still, he mustiness be given credit for his serious-mindedness and interest in improving things in his oft-troubled homeland. Musically, Guerra changed directions again for his 1995 crusade Fogaraté. This album corporate more of the progressively democratic African soukous music. It became quite popular. His 1998 loss Ni Es Lo Mismo Ni Es Igual garnered Guerra three Grammys for Best Merengue Performance, Best Tropical Song for "El Niagara en Bicicleta," and for Best Engineered Album at the low annual Latin Grammy Awards in fall 2000.
Friday, 13 June 2008
Fink
Artist: Fink
Genre(s):
Electronic
Rock
Electronic
Rock
Discography:
Distance and Time
Year: 2007
Tracks: 9
Acoustic Soul
Year: 2006
Tracks: 15
Fresh Produce
Year: 2000
Tracks: 10
Fink is the recording sobriquet of Finian Greenhall, wHO has made the unlikely musical travel from beingness an ambient techno trip-hop creative person to a serious singer/songwriter in less than a x. Born in Bristol, England, Greenhall was taken up with guitar as a teenager, thirstily exploring the indie setting. Then he ascertained raving, and the guitars went out the window as he immersed himself wholly in ambient techno. Greenhall recorded an record album of techno beat generation with Lee Jones (aka Hefner) that was finally released under the make EVA by Kickin? Records in 1995. The record attracted the attention of Ninja Tune Records, which gestural Greenhall as a trip-hop artist. Billing himself as Fink, Greenhall released a pair of EPs, 1997's Finkfunk and 1998's Presence Side Blunt Side, on Ninja Tune's Ntune imprint, then delivered the full-length Fresh Produce in 2000. But Fink was undergoing a ocean change, and had picked up the guitar over again. By the fourth dimension the folky and acoustic-based Biscuits for Breakfast was released (again on the Ntune label) in 2006, Fink had completed the transformation from electronica artist into a fully fledged singer/songwriter, a move that ab initio baffled his fan base.
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